L8P (p.Leu8Pro) variant of RAMP1 (O60894)
L8P (p.Leu8Pro) in RAMP1 (O60894) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
L8P (p.Leu8Pro) variant details
- p.Leu8Pro
- gnomAD 2-237859698-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.216
- REVEL 0.11
- CADD 20.40
- PolyPhen-2 0.31
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available