L8I (p.Leu8Ile) variant of RAMP1 (O60894)
L8I (p.Leu8Ile) in RAMP1 (O60894) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
L8I (p.Leu8Ile) variant details
- p.Leu8Ile
- gnomAD 2-237859697-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.01
- CADD 11.80
- PolyPhen-2 0.09
- SIFT 0.16
- Population evidence available
- Structural context available
- Literature evidence available