L41F (p.Leu41Phe) variant of RAMP1 (O60894)
L41F (p.Leu41Phe) in RAMP1 (O60894) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
L41F (p.Leu41Phe) variant details
- p.Leu41Phe
- ExAC rs768826156
- TOPMed rs768826156
- gnomAD rs768826156
- Missense
- Variant Prioritization Score for Impact Estimate 0.419
- REVEL 0.32
- CADD 21.10
- PolyPhen-2 1.00
- SIFT 0.06
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available