L21H (p.Leu21His) variant of RAMP1 (O60894)
L21H (p.Leu21His) in RAMP1 (O60894) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
L21H (p.Leu21His) variant details
- p.Leu21His
- gnomAD 2-237877231-CCTCT
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.243
- CADD 22.90
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available