H19Y (p.His19Tyr) variant of RAMP1 (O60894)
H19Y (p.His19Tyr) in RAMP1 (O60894) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
H19Y (p.His19Tyr) variant details
- p.His19Tyr
- TOPMed rs1028323509
- gnomAD rs1028323509
- Missense
- Variant Prioritization Score for Impact Estimate 0.331
- REVEL 0.05
- CADD 15.00
- PolyPhen-2 0.56
- SIFT 0.12
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available