G60S (p.Gly60Ser) variant of RAMP1 (O60894)
G60S (p.Gly60Ser) in RAMP1 (O60894) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
G60S (p.Gly60Ser) variant details
- p.Gly60Ser
- ExAC rs749409676
- gnomAD rs749409676
- Missense
- Variant Prioritization Score for Impact Estimate 0.25
- REVEL 0.07
- CADD 20.50
- PolyPhen-2 0.32
- SIFT 0.26
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available