G60R (p.Gly60Arg) variant of RAMP1 (O60894)
G60R (p.Gly60Arg) in RAMP1 (O60894) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
G60R (p.Gly60Arg) variant details
- p.Gly60Arg
- gnomAD 2-237877349-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.337
- REVEL 0.20
- CADD 23.30
- PolyPhen-2 0.89
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available