G12S (p.Gly12Ser) variant of RAMP1 (O60894)
G12S (p.Gly12Ser) in RAMP1 (O60894) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
G12S (p.Gly12Ser) variant details
- p.Gly12Ser
- Ensembl rs2062113358
- Missense
- Variant Prioritization Score for Impact Estimate 0.259
- REVEL 0.04
- CADD 16.40
- PolyPhen-2 0.00
- SIFT 0.31
- Most common in the Non-Finnish European population (allele frequency 9.4e-07)
- Structural context available