F22L (p.Phe22Leu) variant of RAMP1 (O60894)
F22L (p.Phe22Leu) in RAMP1 (O60894) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
F22L (p.Phe22Leu) variant details
- p.Phe22Leu
- 1000Genomes rs201860745
- ExAC rs201860745
- TOPMed rs201860745
- gnomAD rs201860745
- Missense
- Variant Prioritization Score for Impact Estimate 0.0651
- REVEL 0.02
- CADD 7.77
- PolyPhen-2 0.00
- SIFT 0.63
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available