D58E (p.Asp58Glu) variant of RAMP1 (O60894)
D58E (p.Asp58Glu) in RAMP1 (O60894) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
D58E (p.Asp58Glu) variant details
- p.Asp58Glu
- ExAC rs780204782
- gnomAD rs780204782
- Missense
- Variant Prioritization Score for Impact Estimate 0.338
- REVEL 0.22
- CADD 24.20
- PolyPhen-2 0.93
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available