C57Y (p.Cys57Tyr) variant of RAMP1 (O60894)
C57Y (p.Cys57Tyr) in RAMP1 (O60894) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
C57Y (p.Cys57Tyr) variant details
- p.Cys57Tyr
- ExAC rs770143286
- TOPMed rs770143286
- gnomAD rs770143286
- Missense
- Variant Prioritization Score for Impact Estimate 0.769
- REVEL 0.77
- CADD 25.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available