C27Y (p.Cys27Tyr) variant of RAMP1 (O60894)
C27Y (p.Cys27Tyr) in RAMP1 (O60894) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
C27Y (p.Cys27Tyr) variant details
- p.Cys27Tyr
- cosmic curated COSV10879
- ExAC rs755710265
- gnomAD rs755710265
- Missense
- Variant Prioritization Score for Impact Estimate 0.46
- REVEL 0.36
- CADD 24.60
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available