A50T (p.Ala50Thr) variant of RAMP1 (O60894)
A50T (p.Ala50Thr) in RAMP1 (O60894) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
A50T (p.Ala50Thr) variant details
- p.Ala50Thr
- gnomAD rs2062317197
- Missense
- Variant Prioritization Score for Impact Estimate 0.186
- REVEL 0.06
- CADD 14.80
- PolyPhen-2 0.03
- SIFT 0.19
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available