A4T (p.Ala4Thr) variant of RAMP1 (O60894)
A4T (p.Ala4Thr) in RAMP1 (O60894) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
A4T (p.Ala4Thr) variant details
- p.Ala4Thr
- TOPMed rs1191319497
- gnomAD rs1191319497
- Missense
- Variant Prioritization Score for Impact Estimate 0.112
- REVEL 0.01
- CADD 12.20
- PolyPhen-2 0.04
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available