T8I (p.Thr8Ile) variant of RAG1 (P15918)
T8I (p.Thr8Ile) in RAG1 (P15918) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
T8I (p.Thr8Ile) variant details
- p.Thr8Ile
- Ensembl rs1377547190
- Missense
- Variant Prioritization Score for Impact Estimate 0.17
- REVEL 0.08
- MetaLR 0.14
- MetaSVM -0.96
- CADD 12.90
- PolyPhen-2 0.02
- SIFT 0.02
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available