S37Y (p.Ser37Tyr) variant of RAG1 (P15918)
S37Y (p.Ser37Tyr) in RAG1 (P15918) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
S37Y (p.Ser37Tyr) variant details
- p.Ser37Tyr
- gnomAD rs1362347641
- Missense
- Variant Prioritization Score for Impact Estimate 0.554
- REVEL 0.39
- MetaLR 0.62
- MetaSVM 0.26
- CADD 24.90
- PolyPhen-2 0.87
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available