P63L (p.Pro63Leu) variant of RAG1 (P15918)
P63L (p.Pro63Leu) in RAG1 (P15918) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
P63L (p.Pro63Leu) variant details
- p.Pro63Leu
- ExAC rs754373829
- gnomAD rs754373829
- Missense
- Variant Prioritization Score for Impact Estimate 0.29
- REVEL 0.10
- MetaLR 0.30
- MetaSVM -0.61
- CADD 20.80
- PolyPhen-2 0.00
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available