P57S (p.Pro57Ser) variant of RAG1 (P15918)
P57S (p.Pro57Ser) in RAG1 (P15918) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data, published literature, and structural context.
P57S (p.Pro57Ser) variant details
- p.Pro57Ser
- gnomAD 11-36573473-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.065
- REVEL 0.06
- CADD 2.27
- PolyPhen-2 0.00
- SIFT 0.31
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available