P15S (p.Pro15Ser) variant of RAG1 (P15918)
P15S (p.Pro15Ser) in RAG1 (P15918) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
P15S (p.Pro15Ser) variant details
- p.Pro15Ser
- ExAC rs763134083
- TOPMed rs763134083
- gnomAD rs763134083
- Missense
- Variant Prioritization Score for Impact Estimate 0.427
- REVEL 0.23
- MetaLR 0.36
- MetaSVM -0.57
- CADD 22.60
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available