P15R (p.Pro15Arg) variant of RAG1 (P15918)
P15R (p.Pro15Arg) in RAG1 (P15918) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
P15R (p.Pro15Arg) variant details
- p.Pro15Arg
- TOPMed rs1187342308
- gnomAD rs1187342308
- Missense
- Variant Prioritization Score for Impact Estimate 0.548
- REVEL 0.43
- MetaLR 0.50
- MetaSVM 0.05
- CADD 24.40
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available