H20Y (p.His20Tyr) variant of RAG1 (P15918)
H20Y (p.His20Tyr) in RAG1 (P15918) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
H20Y (p.His20Tyr) variant details
- p.His20Tyr
- gnomAD rs1235434764
- Missense
- Variant Prioritization Score for Impact Estimate 0.269
- REVEL 0.16
- MetaLR 0.26
- MetaSVM -0.73
- CADD 19.10
- PolyPhen-2 0.00
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available