G55R (p.Gly55Arg) variant of RAG1 (P15918)
G55R (p.Gly55Arg) in RAG1 (P15918) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
G55R (p.Gly55Arg) variant details
- p.Gly55Arg
- gnomAD rs1850779366
- Missense
- Variant Prioritization Score for Impact Estimate 0.429
- REVEL 0.31
- MetaLR 0.50
- MetaSVM -0.10
- CADD 23.30
- PolyPhen-2 1.00
- SIFT 0.42
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available