G55E (p.Gly55Glu) variant of RAG1 (P15918)
G55E (p.Gly55Glu) in RAG1 (P15918) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
G55E (p.Gly55Glu) variant details
- p.Gly55Glu
- ExAC rs767765877
- gnomAD rs767765877
- Missense
- Variant Prioritization Score for Impact Estimate 0.329
- REVEL 0.20
- MetaLR 0.27
- MetaSVM -0.51
- CADD 21.60
- PolyPhen-2 1.00
- SIFT 1.00
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available