F25L (p.Phe25Leu) variant of RAG1 (P15918)
F25L (p.Phe25Leu) in RAG1 (P15918) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
F25L (p.Phe25Leu) variant details
- p.Phe25Leu
- Ensembl rs2133292669
- Missense
- Variant Prioritization Score for Impact Estimate 0.517
- REVEL 0.50
- MetaLR 0.38
- MetaSVM -0.12
- CADD 24.30
- PolyPhen-2 0.29
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available