V25C (p.Val25Cys) variant of RAD51C (O43502)
V25C (p.Val25Cys) in RAD51C (O43502) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
V25C (p.Val25Cys) variant details
- p.Val25Cys
- rs2047807048
- gnomAD 17-58692706-A-AGC
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.244
- CADD 23.10
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available