F17F (p.Phe17Phe) variant of RAD51C (O43502)
F17F (p.Phe17Phe) in RAD51C (O43502) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
F17F (p.Phe17Phe) variant details
- p.Phe17Phe
- rs1598448876
- gnomAD 17-58692694-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.175
- AlphaMissense 0.67
- MetaLR 0.03
- MetaSVM -0.98
- CADD 9.82
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available