V51V (p.Val51Val) variant of PTPN11 (Q06124)
V51V (p.Val51Val) in PTPN11 (Q06124) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
V51V (p.Val51Val) variant details
- p.Val51Val
- gnomAD 12-112450333-C-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.266
- CADD 9.44
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available