T12T (p.Thr12Thr) variant of PTPN11 (Q06124)
T12T (p.Thr12Thr) in PTPN11 (Q06124) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
T12T (p.Thr12Thr) variant details
- p.Thr12Thr
- rs760086740
- gnomAD 12-112446297-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.158
- CADD 10.90
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available
- Literature evidence available