P33P (p.Pro33Pro) variant of PTPN11 (Q06124)
P33P (p.Pro33Pro) in PTPN11 (Q06124) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, published literature, and structural context.
P33P (p.Pro33Pro) variant details
- p.Pro33Pro
- rs2135856472
- gnomAD 12-112446360-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.537
- CADD 13.90
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available