V9A (p.Val9Ala) variant of PTEN (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-)

Name: PTEN V9A (p.Val9Ala) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-20
License: https://catvariant.com/terms-of-use

V9A (p.Val9Ala) in PTEN (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.

V9A (p.Val9Ala) variant details

p.Val9Ala
gnomAD 10-87864026-T-C
Missense
Variant Prioritization Score for Impact Estimate 0.46
CADD 20.70
SIFT 0.03
Population evidence available
Structural context available
PTEN VAMP-seq Fill-in: score 0.762
Literature evidence available