T26K (p.Thr26Lys) variant of PTEN (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-)
T26K (p.Thr26Lys) in PTEN (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
T26K (p.Thr26Lys) variant details
- p.Thr26Lys
- gnomAD 10-87864086-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.678
- CADD 19.40
- Population evidence available
- Structural context available
- PTEN VAMP-seq Fill-in: score 0.471
- Literature evidence available