T26A (p.Thr26Ala) variant of PTEN (P60484)
T26A (p.Thr26Ala) in PTEN (P60484) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
T26A (p.Thr26Ala) variant details
- p.Thr26Ala
- gnomAD 10-87864028-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.658
- ESM-1b 1.00
- AlphaMissense 0.82
- CADD 20.70
- Population evidence available
- Structural context available
- PTEN VAMP-seq Fill-in: score 0.471
- Literature evidence available