T26A (p.Thr26Ala) variant of PTEN (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-)
T26A (p.Thr26Ala) in PTEN (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
T26A (p.Thr26Ala) variant details
- p.Thr26Ala
- gnomAD 10-87864028-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.562
- CADD 20.70
- SIFT 0.31
- Population evidence available
- Structural context available
- PTEN VAMP-seq Fill-in: score 0.471
- Literature evidence available