S10S (p.Ser10Ser) variant of PTEN (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-)
S10S (p.Ser10Ser) in PTEN (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S10S (p.Ser10Ser) variant details
- p.Ser10Ser
- gnomAD 10-87864015-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.628
- CADD 14.60
- Population evidence available
- Structural context available
- PTEN VAMP-seq Fill-in: score 0.574
- Literature evidence available