S10P (p.Ser10Pro) variant of PTEN (P60484)
S10P (p.Ser10Pro) in PTEN (P60484) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S10P (p.Ser10Pro) variant details
- p.Ser10Pro
- gnomAD 10-87864013-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.806
- ESM-1b 1.00
- AlphaMissense 1.00
- CADD 15.00
- Population evidence available
- Structural context available
- PTEN VAMP-seq Fill-in: score 0.574
- Literature evidence available