R15M (p.Arg15Met) variant of PTEN (P60484)
R15M (p.Arg15Met) in PTEN (P60484) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
R15M (p.Arg15Met) variant details
- p.Arg15Met
- gnomAD 10-87864008-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.483
- ESM-1b 1.00
- AlphaMissense 1.00
- CADD 15.90
- Population evidence available
- Structural context available
- PTEN VAMP-seq Fill-in: score 1.65
- Literature evidence available