I4M (p.Ile4Met) variant of PTEN (P60484)
I4M (p.Ile4Met) in PTEN (P60484) is a missense change. Clinical records from EBI and UniProt describe it as likely benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes experimental measurements and structural context.
I4M (p.Ile4Met) variant details
- p.Ile4Met
- Ensembl rs2132145422
- Likely benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.269
- ESM-1b 0.00
- AlphaMissense 0.09
- EBI: Likely benign
- UniProt: Likely benign
- Structural context available
- PTEN VAMP-seq Fill-in: score 1.65