G20W (p.Gly20Trp) variant of PTEN (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-)
G20W (p.Gly20Trp) in PTEN (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G20W (p.Gly20Trp) variant details
- p.Gly20Trp
- gnomAD 10-87863959-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.564
- CADD 20.10
- SIFT 0.00
- Population evidence available
- Structural context available
- PTEN VAMP-seq Combined: score 0.872
- Literature evidence available