G20W (p.Gly20Trp) variant of PTEN (P60484)
G20W (p.Gly20Trp) in PTEN (P60484) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G20W (p.Gly20Trp) variant details
- p.Gly20Trp
- gnomAD 10-87863959-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.676
- ESM-1b 1.00
- AlphaMissense 1.00
- CADD 20.10
- Population evidence available
- Structural context available
- PTEN VAMP-seq Combined: score 0.872
- Literature evidence available