D19Y (p.Asp19Tyr) variant of PTEN (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-)

Name: PTEN D19Y (p.Asp19Tyr) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-20
License: https://catvariant.com/terms-of-use

D19Y (p.Asp19Tyr) in PTEN (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-) is a missense change. Clinical records from EBI and UniProt describe it as pathogenic in the context of in malignant melanoma. The record also includes experimental measurements and structural context.

D19Y (p.Asp19Tyr) variant details

p.Asp19Tyr
Ensembl rs121909233
Pathogenic
in malignant melanoma
Missense
EBI: Pathogenic (in malignant melanoma)
UniProt: Pathogenic (in malignant melanoma)
Structural context available
PTEN VAMP-seq Fill-in: score 0.742