A3C (p.Ala3Cys) variant of PTEN (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-)
A3C (p.Ala3Cys) in PTEN (Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The record also includes experimental measurements and structural context.
A3C (p.Ala3Cys) variant details
- p.Ala3Cys
- NCI-TCGA Cosmic COSV6428
- NCI-TCGA Cosmic COSV6429
- Variant assessed as somatic; moderate impact.
- Missense
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available
- PTEN VAMP-seq Combined: score 0.968