S19Y (p.Ser19Tyr) variant of PRKN (O60260)
S19Y (p.Ser19Tyr) in PRKN (O60260) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The record also includes variant effect predictions, experimental measurements, and structural context.
S19Y (p.Ser19Tyr) variant details
- p.Ser19Tyr
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- MetaLR 0.37
- MetaSVM -0.60
- SIFT 0.04
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available
- Parkin (PRKN) cellular abundance: score 0.855