T25P (p.Thr25Pro) variant of PRKCH (Protein kinase C eta type)
T25P (p.Thr25Pro) in PRKCH (Protein kinase C eta type) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
T25P (p.Thr25Pro) variant details
- p.Thr25Pro
- gnomAD rs1305111487
- Missense
- Variant Prioritization Score for Impact Estimate 0.617
- REVEL 0.62
- ESM-1b 1.00
- AlphaMissense 0.52
- MetaLR 0.52
- MetaSVM 0.13
- CADD 26.40
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available