S32P (p.Ser32Pro) variant of PRKCH (Protein kinase C eta type)
S32P (p.Ser32Pro) in PRKCH (Protein kinase C eta type) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
S32P (p.Ser32Pro) variant details
- p.Ser32Pro
- Ensembl rs1054017071
- Missense
- Variant Prioritization Score for Impact Estimate 0.393
- REVEL 0.16
- ESM-1b 1.00
- AlphaMissense 0.26
- MetaLR 0.05
- MetaSVM -1.17
- CADD 28.40
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available