R22S (p.Arg22Ser) variant of PRKCB (Protein kinase C beta type)
R22S (p.Arg22Ser) in PRKCB (Protein kinase C beta type) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data, published literature, and structural context.
R22S (p.Arg22Ser) variant details
- p.Arg22Ser
- gnomAD 16-23836239-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.761
- CADD 27.80
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available