R22L (p.Arg22Leu) variant of PRKCB (Protein kinase C beta type)
R22L (p.Arg22Leu) in PRKCB (Protein kinase C beta type) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data, published literature, and structural context.
R22L (p.Arg22Leu) variant details
- p.Arg22Leu
- gnomAD 16-23836240-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.792
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available