R19L (p.Arg19Leu) variant of PRKCB (Protein kinase C beta type)
R19L (p.Arg19Leu) in PRKCB (Protein kinase C beta type) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data and structural context.
R19L (p.Arg19Leu) variant details
- p.Arg19Leu
- cosmic curated COSV57780
- Missense
- Variant Prioritization Score for Impact Estimate 0.761
- CADD 28.60
- PolyPhen-2 0.88
- SIFT 0.06
- Population evidence available
- Structural context available