K45E (p.Lys45Glu) variant of PRKCB (Protein kinase C beta type)
K45E (p.Lys45Glu) in PRKCB (Protein kinase C beta type) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data, published literature, and structural context.
K45E (p.Lys45Glu) variant details
- p.Lys45Glu
- gnomAD 16-23836308-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.641
- CADD 29.70
- PolyPhen-2 0.94
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available