C50S (p.Cys50Ser) variant of PRKCB (Protein kinase C beta type)
C50S (p.Cys50Ser) in PRKCB (Protein kinase C beta type) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
C50S (p.Cys50Ser) variant details
- p.Cys50Ser
- cosmic curated COSV57804
- gnomAD rs1325263692
- Missense
- Variant Prioritization Score for Impact Estimate 0.77
- CADD 29.60
- PolyPhen-2 0.97
- SIFT 0.00
- Population evidence available
- Structural context available