T61R (p.Thr61Arg) variant of POR (NADPH--cytochrome P450 reductase)
T61R (p.Thr61Arg) in POR (NADPH--cytochrome P450 reductase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
T61R (p.Thr61Arg) variant details
- p.Thr61Arg
- rs1403638902
- gnomAD 7-75954177-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.238
- REVEL 0.06
- CADD 18.90
- PolyPhen-2 0.13
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available
- Literature evidence available