T59A (p.Thr59Ala) variant of POR (NADPH--cytochrome P450 reductase)
T59A (p.Thr59Ala) in POR (NADPH--cytochrome P450 reductase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
T59A (p.Thr59Ala) variant details
- p.Thr59Ala
- rs781793249
- gnomAD 7-75954164-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.322
- REVEL 0.06
- AlphaMissense 0.08
- MetaLR 0.09
- MetaSVM -1.05
- CADD 17.80
- PolyPhen-2 0.00
- Population evidence available
- Structural context available
- Literature evidence available