T26K (p.Thr26Lys) variant of POR (NADPH--cytochrome P450 reductase)
T26K (p.Thr26Lys) in POR (NADPH--cytochrome P450 reductase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
T26K (p.Thr26Lys) variant details
- p.Thr26Lys
- gnomAD 7-75954078-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.149
- REVEL 0.06
- CADD 7.41
- PolyPhen-2 0.06
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available